Thermo Finnigan LCQ Advantage MAX LC/MS
The Thermo Finnigan LCQ Advantage MAX is the workhorse ion trap mass spectrometer for high productivity LC/MS/MS results and is easily upgraded to MSn performance.
The Finnigan LCQ Advantage MAX now features the universal Ion Max source that allows simple tool-less switching of ionization probes. Ion Sweep™ gas reduces chemical noise, while a removable ion capillary tube allows for vent-free source maintenance.
Reliability, combined with ease-of-use, make the Finnigan LCQ Advantage MAX an ideal match for the routine HPLC environment. Library searchable MS/MS spectra facilitate unequivocal identification of analytes present in complex matrices. Seamless integration to the Finnigan Surveyor™ and other LC systems, and powerful data analysis capabilities ensure maximum productivity reducing analytical development time within your laboratory.
- Universal Ion Max™ source
- Reliability and ease of operation for high productivity LC/MS/MS
- Integrates seamlessly with LC systems
- Unequivocal identification of analytes from library searchable MS/MS spectra
- Optional MSn capability
Hardware Features:
Ion Max API Source
- Enhanced sensitivity and ruggedness
- Ion Sweep gas reduces chemical noise
- 60° interchangeable ion probe orientation
- Removable metal ion capillary tube provides vent-free maintenance
Standard Features
- Syringe pump for direct sample infusion
- Fully-automated tuning and signal optimization
Vacuum System
- Differentially-pumped vacuum system to 10-5 Torr
- “Dual flow” turbomolecular pump design controls vacuum in two regions
- High-performance roughing pump designed to back up turbomolecular pump
- Precision-engineered, high-vacuum cast aluminum analyzer chamber
Detection System
- Patented, post-acceleration conversion dynode with ±15 kV applied voltage for efficient detection of positive or
negative ions - Off-axis continuous dynode electron multiplier with extended dynamic range
- Unique direct mounting of the multiplier to the electrometer PCB reduces electrical noise
- Digital electronic noise discrimination
This system includes:
- Computer
- Xcalibur Software
- Edwards E2M30 Vacuum Pump
- LCQ Advantage LCMS
System Specifications
MS/MS Sensitivity Electrospray Ionization (ESI) – A 2 μL loop injection of a 5-pg/μL solution of reserpine (10 picograms [16 femtomoles] total sample) at a flow of 350 μL/min of 50% isopropyl alcohol/50% water will produce a minimum signal-to-noise ratio of 10:1 for the transition of the unit isolated protonated molecular ion at m/z 609 to the largest product ion, when the mass spectrometer is operated at unit resolution in the full-scan MS/MS mode, scanning the product ion spectrum from m/z 165-615.
Atmospheric Pressure Chemical Ionization (APCI) – A 2 μL loop injection of a 5-pg/μL solution of reserpine (10 picograms [16 femtomoles] total sample) at a flow of 400 μL/min of 50% isopropyl alcohol/50% water will produce a minimum signal-tonoise ratio of 10:1 for the transition of the unit isolated protonated molecular ion at m/z 609 to the largest product ion, when the mass spectrometer is operated at unit resolution in the full-scan MS/MS mode, scanning the product ion spectrum from m/z 165-615.
Installation Requirements
- One 230 Vac ±10.0%, 50/60 Hz, single phase, with earth ground dedicated to the instrument
- Mechanical pump powered from Finnigan LCQ Advantage
- 120 or 230 Vac single phase,with earth ground for the data system
Gas
- One high-purity (99% pure) nitrogen gas supply for the API source
- One ultra-high-purity helium gas supply (99.998% pure) with less than 1 ppm each of water, oxygen, and total hydrocarbons for the mass analyzer
Environment
- System averages 8000 Btu/h (2300 W) output when considering air conditioning needs
- Operating environment must be 15-27 °C (59-80 °F) and relative humidity must be 40-80% with no condensation
- Optimum operating temperature is 18-21°C (65-70 °F)
Dimensions/Weight
- MS: 56 cm × 65 cm × 76 cm (h × w × d)
- MS: ~113 kg
- Roughing Pump: 38.6 kg
Performance Specifications
Mass Range
- m/z 50 – 2000
Scan Power
- MS and MS/MS standard
- Upgradeable to MSn, for n = 1 to 10
MS Communication Protocols
- Ethernet
- Contact Closure
- Start In/Out
- Ready In/Out
