Agilent 6460C (6470, 6490, 6495) Triple Quadruple LCMS with 1260 Infinity II HPLC System

Manufacturer: Agilent Technologies Model: 1260 Infinity II G7104C Flexible Pump / 1260 Infinity II G7116A MCT / 1260 Infinity II G7167A Multisampler / 1260 Infinity II LC Series HPLC System / 6460C QQQ LCMS Condition: Used Warranty: 30 day Test Performed: Listing ID# 40888
System Includes:
  • Agilent 6460C Triple Quadruple LCMS
    • Agilent LC/MSD API-Electrospray
  • Agilent 1260 Infinity II HPLC
    • Agilent 1260 Infinity II G7104C Flexible Quaternary Pump
    • Agilent 1260 Infinity II G7167A Multisampler
    • Agilent 1260 Infinity II G7116A MCT -Multicolumn Thermostat
  • Roughing Pump
  • Computer
  • Cables and connectors

Agilent 6460C QQQ Triple Quadrupole LC/MS

The Agilent 6460C QQQ Triple Quadrupole LC/MS System is equipped with Agilent Jet Stream Technology to enable enhanced sensitivity. The 6460 provides a fast and robust solution to simultaneously quantify, screen, and confirm analytes in the laboratory.

Unprecedented sensitivity and value

Whether you are quantifying pharmaceutical candidates, measuring trace-level environmental or food contaminants, or confirming biomarkers, the Agilent 6400 Series Triple Quadrupole LC/MS systems offer greater sensitivity, productivity, and value than ever before.

Agilent 1260 Infinity II HPLC System

1260 Infinity II Flexible Pump

The 1260 Infinity II Flexible Pump is a quaternary UHPLC pump that provides gradient formation and solvent blending from up to four solvents. This pump enables quaternary solvent delivery at pressures up to 800 bar and flow rates up to 5 mL/min.

The 1260 Infinity II Flexible Pump combines high performance and simplified operation with highest flexibility in automated gradient formation and solvent blending. This pump also facilitates seamless method transfer using ISET and automated buffer blending.

1260 Infinity II Multisampler

The 1260 Infinity II Multisampler is a multipurpose autosampler that handles vials and microplates. Injecting at pressures up to 600 or 800 bar, the Multisampler is a compact module with a capacity of up to 6,144 samples, all within the footprint of an Agilent LC stack.

The 1260 Infinity II Multisampler is optimized for highest flexibility. The unique dual-needle design enables cycle times to be reduced by overlapping sample runs and injection cycles. The multiwash capability reduces carryover to less than 9 ppm.

1260 Infinity II Multicolumn Thermostat (MCT)

The 1260 Infinity II Multicolumn Thermostat (MCT) is a thermostatted HPLC column compartment that provides precise temperature control for up to four columns over a broad temperature range with cooling to 10 degrees below ambient and heating up to 85 °C.

High-pressure valves rated at 800 bar enable a wide range of applications such as automatic selection of up to four columns, sample preparation for analyte enrichment or matrix removal, or alternating column regeneration. The 1260 Infinity II MCT fits perfectly in any InfinityLab LC Series system and can also be combined with earlier 1260 and 1290 Infinity Series modules.

*Triple Quadrupole options available for additional cost:
Agilent 6495A (6460, 6470, 6490) Triple Quadrupole LCMS System
Agilent 6495B (6460, 6470, 6490) Triple Quadrupole LCMS System
Agilent 6490A (6460, 6470, 6495) Triple Quadrupole LCMS System

Note: Various HPLC and UPLC Front End options availablefor additional cost.

Note: Licenses for Agilent’s software products are not transferable. Any customer who purchases Agilent products are advised to contact Agilent for license requirements.

All Brand Names and Logos depicted at our website are the trademarks of the respective companies. We are not their representatives nor authorized resellers.


Agilent 6460C Triple Quadrupole LCMS Features:


  • Greater signal and reduced noise – Agilent Jet Stream technology uses super-heated nitrogen to improve ion generation and desolvation
  • Efficient analysis – fast MRM speeds allow for analysis of over 100 overlapping compounds in a given retention time window
  • Screen, confirm and quantify – Triggered MRM (tMRM) combines fast and sensitive MRM quantitation with the generation of a product ion spectrum for library searching and compound screening and confirmation
  • Fast polarity switching for analysis of both positive and negative ions


Agilent 1260 Infinity II Multisampler Features:


  • Sample drawers are available in three heights to accommodate any combination of sample containers for maximum flexibility
  • Shallow microplate drawers take a maximum load of 16 microplates and up to 6,144 samples for unmatched sample capacity
  • Robotics move microplates and other sample containers from sample hotel to central workspace for seamless automation during sample processing steps and injections
  • Dual-needle setup enables reduction of injection cycle times to mere seconds, virtually eliminating conventional wait times
  • Dual-needle injection paths can be individually optimized for enhanced injection flexibility
  • Multiwash capability flushes the outside surfaces of the injection needle outside with three solvents and uses seat backflush procedures to reduce carryover to less than 9 ppm
  • Integrated sample thermostat, available as option or upgrade, provides cooling and heating from 4 to 40 °C
  • Lights on each drawer indicate loading status, current activity, and accessibility for instant information


Agilent 1260 Infinity II Flexible Pump Features:


  • Low delay volume, extended pressure range up to 800 bar, analytical flow rates up to 5 mL/min, and superior quaternary mixing enables higher precision and accuracy for maximum chromatographic performance
  • Multipurpose valve enables automated software-embedded functionality such as switching the optional mixer in and out, flushing back the inline filter or automated purging for reduced manual interaction
  • Intelligent System Emulation Technology (ISET) enables emulation of existing Agilent 1100, 1200, and 1260 Infinity Series instruments, as well as Waters Alliance, Waters H-Class, and Shimadzu Prominence instruments facilitating seamless method transfer
  • Active damping with independently controllable high-resolution pump drives and firmware-embedded tuning algorithms, as well as switchable Jet Weaver mixers for extra mixing volume, significantly reduce ripple and associated UV noise
  • Proven Inlet Weaver technology offers highest solvent mixing efficiency before solvent reaches the pump head
  • Integrated high efficiency degasser with low internal volume based on PTFE AF technology offers fast change-over of solvents for purging and priming
  • BlendAssist, a software feature in the pump driver, enables convenient, precise, and accurate buffer or additive blending
  • Built-in seal wash keeps maintenance to a minimum, increases longevity and reduces operating costs


Agilent 1260 Infinity II Multicolum Thermostat Features:


  • Peltier cooling and heating with two independent temperature zones from 10 degrees below ambient to 85 °C for maximum application flexibility
  • Up to four 30 cm columns with InfinityLab Quick Connect fittings or precolumns for high column capacity
  • Bio-inert options for heat exchangers and InfinityLab Quick Change valve heads enable analysis of biomolecules
  • Door positions at 90° or 180° provide for superior usability, or door removal for maximum accessibility
  • InfinityLab Quick Connect heat exchangers achieve reproducible precolumn solvent heating
  • InfinityLab Quick Connect fittings facilitate efficient, fast, and convenient column exchange
  • Optional valve drive for activation of user-exchangeable InfinityLab Quick Change valve heads with pressure ratings up to 800 bar
  • Identification of up to four columns with record of type, major parameters, and number of injections for traceable column history

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